It is possible to change the SSL certificate or private key of UnrealIRCdWikipedia: UnrealIRCd is an open-source IRC daemon, originally based on DreamForge, and is available for Unix-like operating systems and Windows. Since the beginning of development on UnrealIRCd c. May 1999, man... without restarting the process. A normal /rehash or HUP does not make the changes take effect, rather you need to use the -ssl flag of /rehash.
/rehash -ssl
Or if you’re rehashing a remote server:
/rehash ServerName* -ssl